St. Anthony of Padua Cathedral, alternatively known as the Sant'Antonio di Padova Cathedral, S. Antonio di Padova, St. Antoine or St. Antuan, is the largest catthedral of the Roman Catholic Church in Istanbul, Turkey. It is located on Istiklal Avenue in the Beyoglu district.
Along with the Catedral of the Holy Spirit (1846) in the Harbiye district, St. Louis of the French (1581) and Santa Maria Draperis in Beyoglu, Sts. Peter and Paul (1841) in Galata, Assumption Church in the Moda quarter of Kadikoy, St. Stephen in Yesilkoy and Bakırköy Church in Bakirkoy, it is one of the most important Catholic churches in Istanbul, and among them has the largest community following its masses.